Human erythrocyte acetylcholinesterase in relation to cell age

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Human Erythrocyte Acetylcholinesterase in Health and Disease.

The biochemical properties of erythrocyte or human red blood cell (RBC) membrane acetylcholinesterase (AChE) and its applications on laboratory class and on research are reviewed. Evidence of the biochemical and the pathophysiological properties like the association between the RBC AChE enzyme activity and the clinical and biophysical parameters implicated in several diseases are overviewed, an...

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Age-dependent decline in erythrocyte acetylcholinesterase activity: correlation with oxidative stress.

BACKGROUND Oxidative stress hypothesis offers a mechanism for the aging process and its involvement in other pathologies such as diabetes and neurodegenerative diseases like Alzheimer. AChE activity in erythrocytes may be considered as a marker of central cholinergic status. The present study was undertaken to (i) determine the activity of erythrocyte AChE as a function of human process (ii) co...

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the effects of zinc and mercury on human erythrocyte acetylcholinestrase activity were studied. blood used in this study was obtained from 24 apparently healthy individuals and after hemolysation, was treted with 3 diferent concentrations of zinc and mercury. significant suppressions in acetylcholinestrase activity were recorded in treated samples by zinc and mercury. when compared to controls ...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1981

ISSN: 0264-6021

DOI: 10.1042/bj1950221